Investigating gene control mechanisms that drive development and disease

and applying lessons learned from these studies to building a better heart.

Welcome to the Boyer Lab

We investigate how the regulation of complex gene circuits informs developmental outcomes using heart as a model system. We also apply these models and methods to develop novel therapeutic strategies for stimulating cardiac tissue repair.

Our ability to combine genomic, genetic, biochemical, and cell biological approaches both in vitro and in vivo allows us to gain a systems level and quantitative understanding of the regulatory circuits in both normal and pathological conditions. Ongoing efforts using tissue engineering to model the 3D architecture of the heart will also lend itself to this effort. More broadly, we discover fundamental principles that can be applied to understanding developmental control mechanisms across systems.

#Congratulations to #Constantine and #Alex on the official #publication of their manuscript!👏👏👏 #teamBoyer
Below is link to #manuscript

Congratulations to Undergrad Meghan Davis for being selected to speak at the Undergrad Research Symposium on January 28, 2021 at 1:00 pm EST!

Looking for an exciting postdoc to study gene regulatory mechanisms that drive cell fate and regeneration? The Boyer lab at MIT is the place for YOU! Please send inquiries directly to lboyer [at] mit [dot] edu.

Excited to welcome new graduate students: Catherine Santina and John Day! They will develop and apply new approaches for studying molecular and cellular changes in cardiac regeneration and regulation of DNA and genome topology during lineage commitment, respectively! WOW!

@boyerlab2 Join our dynamic and talented team! We have openings for postdocs and techs interested in understanding how metabolism and chromatin crosstalk to specify cardiac cell fate using mouse models and hiPSC mediated differentiation! Please email lboyer[at]mit dot edu for information!

Congratulations to Boyer Lab & MIT s
student Meghan Davis for winning the Mitchell Scholarship. #Trailblazer #women #Mitchellscholarship

Thank you to @innoVitroBio for awarding our lab with a FLEXcyte grant! We are so excited to leverage your cutting edge and quantitative platform to solve really important questions in the field for understanding cardiac cell fate and function!

We are thrilled that our work to develop high-throughput Expansion Microscopy was awarded funding from the MIT Jarve Fund! Thank you for the support!

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