Investigating gene control mechanisms that drive development and disease
and applying lessons learned from these studies to building a better heart.
Welcome to the Boyer Lab
We investigate how the regulation of complex gene circuits informs developmental outcomes using heart as a model system. We also apply these models and methods to develop novel therapeutic strategies for stimulating cardiac tissue repair.
Our ability to combine genomic, genetic, biochemical, and cell biological approaches both in vitro and in vivo allows us to gain a systems level and quantitative understanding of the regulatory circuits in both normal and pathological conditions. Ongoing efforts using tissue engineering to model the 3D architecture of the heart will also lend itself to this effort. More broadly, we discover fundamental principles that can be applied to understanding developmental control mechanisms across systems.